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Brainomix eAspects

Brainomix e-CTP

  • CT Perfusion (CTP) scans
  • Stroke detection

 

e-CTP is a software medical device for processing brain CT Perfusion (CTP) scans for stroke patients. e-CTP provides both analysis and viewing capabilities for brain CT Perfusion datasets. ​​

 

The analysis capabilities are for the characterization of perfusion parameters in the image following the injection of a contrast bolus, and visualization of these parameters.​​1

eCTP Viewer

Images shown for illustrative purposes only.

Brainomix 360 is a comprehensive platform designed to support clinicians and their imaging-based treatment decisions at all points across the stroke pathway, from simple imaging to more advanced imaging.

The Brainomix 360 Mobile App allows clinicians to quickly and securely access, preview, and share images and patient data across a network, send messages, make calls, and enhance collaboration for patient care - all designed to optimize workflow, facilitating faster transfer and treatment decisions.​​ ​

Clinical Workflow

CINA (for ICH)

ICH workflow

CINA (for LVO)

LVO workflow

For CalanticTM software version 1.0.0, no prior study will be examined.

*ICH refers to intracranial haemorrhage; SAH to subarachnoid haemorrhage; SDH to subdural haemorrhage; IPH to intraparenchymal haemorrhage; IVH to intraventricular haemorrhage; and EDH to epidural haemorrhage.

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    • Head contrast CT scans (NCCT)
    • Slice thickness​: Maximum 5mm slice thickness recommended. Thin slice acquisitions (e.g. 1mm are supported)
    • Acquisition volume​: As large a coverage as possible when performing CT Perfusion acquisitions on the CT scanner, ideally up to full brain coverage
    • Acquisition mode​: Shuttle mode and jog mode acquisitions are supported. Typically this would mean a sequence of at least 45 seconds
    • Temporal resolution​: One time point (volume) acquired every 1-4 seconds
    • Acquisition timing​: At least 5 seconds baseline captured prior to bolus arrival, and full AIF peak and wash-out from first circulation of the bolus captured. Typically this would mean a sequence time of at least 45 seconds
    • Matrix size​: 512 x 512 recommended
    • Field of view​: Approximately 24cm recommended (typical head CT FOV)
    • Image acquisition parameters​: 70-80 kV​ and 170-400 mAs

    Perfusion volumes, mismatch, and related information:

    Displayed at the top of the page, this section can be scrolled and contains the following details:
     

    • Warnings: 
      • Visible on the left-hand side of the page. 
      • Includes warnings from e-CTP that may affect the accuracy of the results.
    • Summary mismatch map: 
      • Displays the thresholded volume extent on the pre-bolus arrival mean image.
    • Mismatch results: 
      • Derived from the mismatch maps: 
      • Mismatch volume: hypoperfusion volume minus core volume. 
      • Mismatch ratio: hypoperfusion volume divided by core volume. 
      • Relative mismatch: mismatch volume divided by hypoperfusion volume.
    • AIF/VOF curves: 
      • Arterial input function (AIF) and venous output function (VOF) curves. 
      • Displays HU (Hounsfield Unit) values in these vessels over time.
    eCTP output

      Currently not made available with Calantic Viewer. Separately distributed by Bayer.  

      EU risk class and CE marking                
      e-CTP has CE marking and risk class IIa.

      Reimbursement status                
      Not reimbursed.

      Contraindications
      No contraindications given.

      Target Population 
      Adults

      Limitations

      • Results generated by e-CTP should not be used as a standalone diagnosis. ​​
      • e-CTP should only be used by a competent healthcare professional with an understanding of brain CT Perfusion image acquisition and interpretation, as an aid to image interpretation of cerebral perfusion abnormalities.​​
      • e-CTP may not correctly identify perfusion abnormalities in every cerebral CT Perfusion dataset. Users should use their own expertise in cerebral CT Perfusion image interpretation to verify that the software's output is correct.​​
      • e-CTP may not correctly identify perfusion parameters on brain scans containing major anatomical abnormalities (e.g., hydrocephalus, large tumors, intracerebral hemorrhage, craniectomy), and additional care should be taken when reviewing such results.
        1.
        User Manual Version e-CTP-MAN-11.2 - 2024-05-23
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        Other Offerings in the Neuro Service Line

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        Brainomix e-CTA

        • CT Angiography (CTA) scans
        • Stroke detection
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        Brainomix e-ASPECTS

        • Non contrast brain CT
        • Stroke detection