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Quantib

Quantib Prostate

  • Intraprostatic lesions
  • MRI

Quantib Prostate provides the user with processing, visualization, and editing of prostate MRI images. The software can be used for semi-automatic segmentation of anatomical structures and provides volume computations, together with tools for manual editing. PI-RADS scoring is possible using a structured workflow.

Quantib viewer

Images shown for illustrative purposes only.

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~29% and ~21% improved nodules detection

Riverain's AI suppression technology removes structures that can camouflage cancer and lung disease. 1,2

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Higher inter-reader agreement rates2

Clinical Workflow

clearread workflow

For CalanticTM software version 1.0.0 and older versions, no prior study will be examined.

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    Appropriate Series for a T2 Scan

    Acquisition type: 2D, 3D axial or near axial

    Spacing in axial plane: ≤1mm

    Recommended spacing in axial plane: 0.35mm - 0.78mm

    Slice thickness: Any

    Recommended Slice thickness: ≤3mm

    Slice gap: Any

    Recommended Slice gap: No slice gap

     

    Appropriate Series for ADC and highest b-value scan

    Acquisition type: 2D, 3D axial or near axial

    Spacing in axial plane: ≤2mm

    Slice thickness: ≤4mm

    B-Value of high b-value DWI scan: ≥800 s/mm2

    Recommended B-Value of high b-value DWI scan: ≥1400 s/mm2

     

    Appropriate Series for DCE scan

    Acquisition type: 2D, 3D axial or near axial

    Quantib Prostate creates DICOM output that contains the following reports.

     

    • A secondary capture series of the T2 image with the prostate and ROI contours
    • A secondary capture series of the T2 image with the prostatic sub-regions and ROI contours
    • A secondary capture series of a 3D rendering of the ROI and prostate segmentations
    • A DICOM segmentation series of the prostate segmentation
    • A DICOM segmentation series of the ROI segmentations
    • Optionally, a DICOM RTStruct series of the prostate and ROI contours. Consult with a service and installation engineer to configure the RTStruct format matching your clinical workflow.
    • Optionally, secondary capture series of an image-on-image overlay, which can be the biparametric combination image.
    • A report is created, which can be exported as PDF format embedded in a DICOM file and/or as a DICOM secondary capture series. The report contains:
      - Patient and study information
      - Prostate segmentation results of
      • Prostate volume
      • PSA
      • PSA density
    • General findings
    • Comments as written in the text box
    • A lesion summary, with the PI-RADS score, maximal axial dimension, and PI-RADS sector per lesion, and the location of each lesion indicated on the sector map. Additionally, four views of a 3D rendering of the lesions in the prostate are shown. Note that lesions are sorted on highest to lowest PI-RADS score, followed by decreasing axial dimension, and that the order therefore does not necessarily match the order in the user interface.
    • A detailed section per lesion, specifying:
      - Slice numbers matching the Quantib Prostate user interaction interface oContour on screenshot of T2 (in axial and sagittal view), ADC, and high b-value scan oVolume
      - Maximal axial dimension oADC value (average and standard deviation) oPI-RADS sector
      - PI-RADS score (per sequence and overall)
      - Lesion findings as entered in the front-end
      - Kinetic curves if a DCE scan is available

      Currently not made available with Calantic Viewer. Separately distributed by Bayer.

       

      EU risk class and CE marking
      Quantib Prostate has CE marking (CE0344) and risk class IIb.

      Reimbursement status
      Not reimbursed.

      Contraindications
      No contraindications given.

      Target population
      Patients 18 years and older.

      Intended user
      Trained medical professionals, including radiology professionals, physicians, radiographers, radiologic technologists, and clinical researchers working with radiology images.

      Limitations
      The presence of artifacts, pathologies, noise, and treatment-induced features has a negative effect on output accuracy. The software is not validated for use in patients after full or partial prostatectomy, or after radiation treatment.

        1.
        Instructions for Use Quantib Prostate, software version 2.1
        2.
        Cipollari S, Pecoraro M, Forookhi A, et al. Biparametric prostate MRI: impact of a deep learning-based software and of quantitative ADC values on the inter-reader agreement of experienced and inexperienced readers. Radiol Med. 2022 Nov;127(11):1245-1253. doi: 10.1007/s11547-022-01555-9. Epub 2022 Sep 17. PMID: 36114928; PMCID: PMC9587977.
        3.
        Forookhi A, Laschena L, Pecoraro M, et al. Bridging the experience gap in prostate multiparametric magnetic resonance imaging using artificial intelligence: A prospective multi-reader comparison study on inter-reader agreement in PI-RADS v2.1, image quality and reporting time between novice and expert readers. Eur J Radiol. 2023 Apr;161:110749. doi: 10.1016/j.ejrad.2023.110749. Epub 2023 Feb 19. PMID: 36812699.
        4.
        Faiella E, Vertulli D, Esperto F, et al. Quantib Prostate Compared to an Expert Radiologist for the Diagnosis of Prostate Cancer on mpMRI: A Single-Center Preliminary Study. Tomography. 2022 Aug 13;8(4):2010-2019. doi: 10.3390/tomography8040168. PMID: 36006066; PMCID: PMC9415513.
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        Now available as part of Calantic’s Prostate Service Line. Contact us today to learn more.

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