IB Delta T1 Maps

Performs post-processing of MR T1-weighted images and simplifies post-processing tasks.

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Imaging
  • T1
  • contrast enhancement
  • regions of interest
  • ROI

Output includes an anatomic image showing the areas of true contrast enhancement.

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IB Delta T1 may provide greater sensitivity for stratifying subpopulations over adjudicated 2D manual delineation of enhancing tumor reads.1

1Schmainda KM, Prah MA, Zhang Z, Snyder BS, Rand SD, Jensen TR, Barboriak DP, Boxerman JL. Quantitative Delta T1 (dT1) as a Replacement for Adjudicated Central Reader Analysis of Contrast-Enhancing Tumor Burden: A Subanalysis of the American College of Radiology Imaging Network 6677/Radiation Therapy Oncology Group 0625 Multicenter Brain Tumor Trial. AJNR Am J Neuroradiol. 2019 Jul;40(7):1132-1139. doi: 10.3174/ajnr.A6110. Epub 2019 Jun 27. PMID: 31248863; PMCID: PMC6620020.

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Can predict early progression comparable with standard 2D manual method but has the potential for substantial time and cost savings for clinical trials.1

1Schmainda KM, Prah MA, Zhang Z, Snyder BS, Rand SD, Jensen TR, Barboriak DP, Boxerman JL. Quantitative Delta T1 (dT1) as a Replacement for Adjudicated Central Reader Analysis of Contrast-Enhancing Tumor Burden: A Subanalysis of the American College of Radiology Imaging Network 6677/Radiation Therapy Oncology Group 0625 Multicenter Brain Tumor Trial. AJNR Am J Neuroradiol. 2019 Jul;40(7):1132-1139. doi: 10.3174/ajnr.A6110. Epub 2019 Jun 27. PMID: 31248863; PMCID: PMC6620020.

 

    Use existing neuro imaging protocols

    Use existing neuro imaging protocols

    Delta T1 maps apply to any neuro exam consisting of pre- and post-contrast T1w images

    References

    References

    1. IB Clinic 2.0 release 21.12 User Manual
    2. Prah et al, Repeatability of Standardized and Normalized Relative CBV, AJNR Am J Neuroradiology, 2015
    3. Hu, et al, Impact of Software Modeling on the Accuracy of Perfusion MRI, AJNR Am J Neuroradiology, 2015
    4. Schmainda et al, Quantitative Delta T1 (dT1), AJNR Am J Neuroradiology, 2019
    5. Schmainda, Diffusion­ weighted MRI as a biomarker for treatment response in glioma, CNS Oncol, 2012

    What Customers Are Saying

    The T1 with contrast is hard to interpret, but I think the Delta T1 says it all.

    Dr Jennifer Connelly
    MD Associate Professor of Neurology and Co-Director of theNeuro-oncology Program at Froedtert and the Medical College of Wisconsill.

    May not reflect a typical user experience; actual results may vary.

    What Customers Are Saying

    When new areas of enhancement are identified, our surgeons and neuro-oncologists want to see IB's Delta T1 maps and standardized rCBV on our patients to guide therpeutic and surgical management. The additional information added by IB's maps to conventional imaging is instrumental in patient management.

    Dr Johr Karis,
    MO Neurocadiologist at Southwest Neuro-lmaging lid.

    May not reflect a typical user experience; actual results may vary.

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    Last Updated: August 2023

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