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IB DCE

Analyzes post-contrast MR images of the brain collected as a series of timepoints over a period during the arrival and washout of the contrast agent.

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Imaging
  • Ktrans
  • Ve
  • Vp
  • VIF

IB DCE generates dynamic contrast enhancement (DCE) parametric images.

Parameters related to tumor vascularity and blood vessel leakiness may be calculated from the series of images. These include the Ktrans transfer constant; extravascular, extra-cellular fractions (ve); and blood plasma fraction (vp).

 

    DCE Perfusion Weighted MR Imaging (DCE-MRI)

    Produces various parameter maps including: K: Transfer constant; IS: Initial Slope (aka Wash-In); WO: Wash­ Out; PE: Peak enhancement; IAUC: Initial Area Under the Curve; TTP: Time-to-Peak; rTTP: Relative Time-to­ Peak

    References

    1. IB Clinic 2.0 release 21.12 User Manual
    2. Prah et al, Repeatability of Standardized and Normalized Relative CBV, AJNR Am J Neuroradiology, 2015
    3. Hu, et al, Impact of Software Modeling on the Accuracy of Perfusion MRI, AJNR Am J Neuroradiology, 2015
    4. Schmainda et al, Quantitative Delta T1 (dT1), AJNR Am J Neuroradiology, 2019
    5. Schmainda, Diffusion­ weighted MRI as a biomarker for treatment response in glioma, CNS Oncol, 2012

    What Customers Are Saying

    We appreciate the speed of IB products and their compatability with PACS. More recently, we have started to use IB products for image-guided surgical planning. We anticipate their use for radiation therapy planning in the near future. Our neurosurgeons, radiation oncologists, and neuro oncologists find perfusion scans and Delta T1 maps of the brain to be very useful, and now routinely write orders to obtain this information.

    Dr. Scott Rand
    Professor of Radiology at Froedtert Health and the Medical College of Wisconsin.

    May not reflect a typical user experience; actual results may vary.

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